SiO2-BaCl2 as a Highly Efficient and Reusable Heterogeneous Catalyst for the One-pot Synthesis of 3,4-dihydropyrimidin-2-(1H)- one/thione Derivatives Under Solvent-free Conditions
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Abstract:
An efficient protocol for the synthesis of 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives via multi-component coupling reaction of aromatic aldehydes, β-ketoester and urea or thiourea under solvent-free conditions using Silica Supported Barium Chloride as a catalyst is described. All prepared compounds with melting points, IR,1H NMR and 13C NMR were identified. High yields, mild conditions, easy availability and reusability were some advantages of this catalyst.
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sio2-bacl2 as a highly efficient and reusable heterogeneous catalyst for the one-pot synthesis of 3,4-dihydropyrimidin-2-(1h)- one/thione derivatives under solvent-free conditions
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Journal title
volume 9 issue 1
pages 95- 101
publication date 2015-11-01
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